Konstantina Stankovic
Konstantina Stankovic, MD, PhD, is a professor and the Chair of Otolaryngology at Stanford School of Medicine. Her research focuses on inner ear pathology, hearing loss mechanisms, and the molecular biology and treatment of vestibular schwannomas. Her work also covers inner ear models for evaluating ototoxicity, stem cell-derived auditory neurons, high-resolution cochlear imaging, and applications of artificial intelligence in otolaryngology and genetic diagnosis.
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Publications
- Proteomic Analysis Identifies Novel Plasma Biomarkers in Patients With Vestibular Schwannoma.
- Establishment of a human inner ear model reveals that gentamicin C2b is substantially less ototoxic than clinical gentamicin.
- Multimodal biomarker landscape in vestibular schwannoma.
- The State of Female Surgeon-Scientists in Otolaryngology-Head and Neck Surgery.
- Genetic Diagnosis and Discovery Enabled by Large Language Models.
- NKG2D upregulation sensitizes tumors to combined anti-PD1 and anti-VEGF therapy and prevents hearing loss.
- A cochlea-sparing strategy for non-invasive control of intracranial schwannomas via peripheral irradiation and anti-PD-1 therapy enhanced by STING activation.
- A plasma metabolomic fingerprint of moderate or severe hearing loss.
- Engineering of functional auditory neurons from human induced pluripotent stem cells.
- Beta-2 Transferrin May Not Be Specific for Presence of Cerebrospinal Fluid in Middle Ear Fluid.
- High resolution, contrast-enhanced X-ray microscopy of the ex vivo human cochlea: technical feasibility and biometric case analysis.
- American Academy of Otolaryngology-Head and Neck Surgery (AAO-HNS) Report on Artificial Intelligence.
- Angiotensin-Receptor Blockers Prevent Vestibular Schwannoma-Associated Hearing Loss.
- NF2 is Essential for Human Endoderm Development.
- Immune profiling of human vestibular schwannoma secretions identifies TNF-α and TWEAK as cytokines with synergistic potential to impair hearing.
- Why Consider Aspirin for the Treatment of Vestibular Schwannoma? A Brief Review and Randomized, Double-Blind, Placebo-Controlled Study Proposal.
- Editorial: Third window syndrome, volume II.
- Scoping review of deep learning research illuminates artificial intelligence chasm in otolaryngology-head and neck surgery.
- The State of High-Resolution Imaging of the Human Inner Ear: A Look Into the Black Box.
- Amplifying Endoplasmic Reticulum Stress With Adenosine Triphosphate-Coated Gold Nanoclusters: A Promising Approach for the Treatment of Vestibular Schwannoma.
- Correction: Immune profiling of human vestibular schwannoma secretions identifies TNF-α and TWEAK as cytokines with synergistic potential to impair hearing.
- Clinical trials in otology and neurotology: state of the science.
- Editorial: Pathobiological defects in sensorineural hearing loss: from identification to rescue.
- Comparison of the rates of emergent otologic adverse events following mRNA COVID-19 versus influenza vaccination: a matched cohort analysis.
- Immune Profiling of Secreted Factors from Human Vestibular Schwannoma Cells and Tumor-associated Macrophages.
- Surgical Considerations in Inner Ear Gene Therapy from Human Temporal Bone Anatomy.
- Tinnitus prevalence, associated characteristics, and related healthcare use in the United States: a population-level analysis.
- Correction: Natarajan et al. Noise-Induced Hearing Loss. J. Clin. Med. 2023, 12 , 2347.
- Human otic progenitor cell models of congenital hearing loss reveal potential pathophysiologic mechanisms of Zika virus and cytomegalovirus infections.
- Dynamic micro-optical coherence tomography enables structural and metabolic imaging of the mammalian cochlea.
- An In Vitro Oxidative Stress Model of the Human Inner Ear Using Human-Induced Pluripotent Stem Cell-Derived Otic Progenitor Cells.
- Enhanced Tumor Control and Hearing Loss Prevention Achieved with Combined Immune Checkpoint Inhibitor and Anti-VEGF Therapy in Vestibular Schwannoma Model.
- Polystyrene nanoplastics affect transcriptomic and epigenomic signatures of human fibroblasts and derived induced pluripotent stem cells: Implications for human health.
- Genome-wide screen of otosclerosis in population biobanks: 27 loci and shared associations with skeletal structure.
- Identification of Immune-Related Candidate Biomarkers in Plasma of Patients with Sporadic Vestibular Schwannoma: Candidate Plasma Biomarkers in Vestibular Schwannoma.
- Associations of Tinnitus Incidence with Use of Tumor Necrosis Factor-Alpha Inhibitors among Patients with Autoimmune Conditions.
- Association of Plasma Metabolomic Biomarkers With Persistent Tinnitus: A Population-Based Case-Control Study.
- Noise-Induced Hearing Loss.
- The Future of Vestibular Schwannoma Management.
- Comparative Transcriptomic Analysis of Archival Human Vestibular Schwannoma Tissue from Patients with and without Tinnitus.
- Potential Ototoxicity of Insulin-like Growth Factor 1 Receptor Signaling Inhibitors: An In Silico Drug Repurposing Study of the Regenerating Cochlear Neuron Transcriptome.
- Promoting Surgeon-Scientists in Otolaryngology-Head and Neck Surgery-From Bench to Bedside.
- miR-431 secreted by human vestibular schwannomas increases the mammalian inner ear's vulnerability to noise trauma.
- Mortui vivos docent: a modern revival of temporal bone plug harvests.
- Current and Emerging Therapies for Chronic Subjective Tinnitus.
- Identification of immune-related candidate biomarkers in plasma of patients with sporadic vestibular schwannoma.
- Genetic Discovery Enabled by A Large Language Model.
- The AAV9 Variant Capsid AAV-F Mediates Widespread Transgene Expression in Nonhuman Primate Spinal Cord After Intrathecal Administration.
- Implementation of Mobile Audiometry During the COVID-19 Pandemic.
- Imbalance and dizziness caused by unilateral vestibular schwannomas correlate with vestibulo-ocular reflex precision and bias.
- Infectious Complications Following Cochlear Implant: Risk Factors, Natural History, and Management Patterns.
- Choice of vector and surgical approach enables efficient cochlear gene transfer in nonhuman primate.
- Human vestibular schwannoma reduces density of auditory nerve fibers in the osseous spiral lamina.
- Sporadic Vestibular Schwannoma Size and Location Do not Correlate With the Severity of Hearing Loss at Initial Presentation.
- Orally administered fluorescent nanosized polystyrene particles affect cell viability, hormonal and inflammatory profile, and behavior in treated mice.
- Celastrol suppresses the growth of vestibular schwannoma in mice by promoting the degradation of β-catenin.
- Magnetic stimulation allows focal activation of the mouse cochlea.
- Association of Stapedotomy Volume and Patient Sex With Better Outcome.
- Toward Personalized Diagnosis and Therapy for Hearing Loss: Insights From Cochlear Implants.
- Reversible contrast enhancement for visualization of human temporal bones using micro computed tomography.
- A fluorescent photoimmunoconjugate for imaging of cholesteatoma.
- Human pluripotent stem cells - Unique tools to decipher the effects of environmental and intracellular plastic pollution on human health.
- Postnatal expression and possible function of RANK and RANKL in the murine inner ear.
- Human induced pluripotent stem cells and CRISPR/Cas-mediated targeted genome editing: Platforms to tackle sensorineural hearing loss.
- New developments in neurofibromatosis type 2 and vestibular schwannoma.
- Initial Method for Characterization of Tympanic Membrane Drug Permeability in Human Temporal Bones In Situ .
- Special Series: Stem Cells and Hearing Loss.
- Osteoporosis, bisphosphonate use, and risk of moderate or worse hearing loss in women.
- Cochlin Deficiency Protects Against Noise-Induced Hearing Loss.
- Losartan prevents tumor-induced hearing loss and augments radiation efficacy in NF2 schwannoma rodent models.
- Re-engineering the Surgeon-Scientist Pipeline: Advancing Diversity and Equity to Fuel Scientific Innovation.
- Two Photon Fluorescence Microscopy of the Unstained Human Cochlea Reveals Organ of Corti Cytoarchitecture.
- Endomicroscopy of the human cochlea using a micro-optical coherence tomography catheter.
- Conductive Hearing Loss in the Hyp Mouse Model of X-Linked Hypophosphatemia Is Accompanied by Hypomineralization of the Auditory Ossicles.
- TMPRSS3 Gene Variants With Implications for Auditory Treatment and Counseling.
- Direct SARS-CoV-2 infection of the human inner ear may underlie COVID-19-associated audiovestibular dysfunction.
- Accelerated Long-Term Hearing Loss Progression After Recovery From Idiopathic Sudden Sensorineural Hearing Loss.
- Molecular and Clinical Significance of Fibroblast Growth Factor 2 in Development and Regeneration of the Auditory System.
- Light-Based Neuronal Activation: The Future of Cranial Nerve Stimulation.
- Combination therapy with mTOR kinase inhibitor and dasatinib as a novel therapeutic strategy for vestibular schwannoma.
- Cigarette Smoking, Smoking Cessation, and Risk of Hearing Loss in Women.
- National Trends in Surgical Resection of Vestibular Schwannomas.
- Regeneration of Cochlear Synapses by Systemic Administration of a Bisphosphonate.
- MMP-14 (MT1-MMP) Is a Biomarker of Surgical Outcome and a Potential Mediator of Hearing Loss in Patients With Vestibular Schwannomas.
- Topical fibroblast growth factor-2 for treatment of chronic tympanic membrane perforations.
- Altered expression of genes regulating inflammation and synaptogenesis during regrowth of afferent neurons to cochlear hair cells.
- Progression of Contralateral Hearing Loss in Patients With Sporadic Vestibular Schwannoma.
- Noncontrast vestibular schwannoma surveillance imaging including an MR cisternographic sequence: is there a need for postcontrast imaging?
- A cerebellopontine angle mouse model for the investigation of tumor biology, hearing, and neurological function in NF2-related vestibular schwannoma.
- Fracture of the Incus Caused by Digital Manipulation of the Ear Canal and its Diagnosis Using Wideband Acoustic Immittance.
- Selective femtosecond laser ablation via two-photon fluorescence imaging through a multimode fiber.
- Periostin and Inflammatory Disease: Implications for Chronic Rhinosinusitis.
- Gene therapy with apoptosis-associated speck-like protein, a newly described schwannoma tumor suppressor, inhibits schwannoma growth in vivo.
- ACUTE OTITIS MEDIA AND ASSOCIATED COMPLICATIONS IN UNITED STATES EMERGENCY DEPARTMENTS.
- Proteome of normal human perilymph and perilymph from people with disabling vertigo.
- A novel microneedle device for controlled and reliable liquid biopsy of the human inner ear.
- Gene Therapy for Human Sensorineural Hearing Loss.
- NLRP3 inflammasome activation in human vestibular schwannoma: Implications for tumor-induced hearing loss.
- Cochlear histopathology in human genetic hearing loss: State of the science and future prospects.
- Cytokine Levels in Inner Ear Fluid of Young and Aged Mice as Molecular Biomarkers of Noise-Induced Hearing Loss.
- Imaging hair cells through laser-ablated cochlear bone.
- Intracochlear Perfusion of Tumor Necrosis Factor-Alpha Induces Sensorineural Hearing Loss and Synaptic Degeneration in Guinea Pigs.
- Periostin as a Biomarker for Nasal Polyps in Chronic Rhinosinusitis.
- Targeting the cMET pathway augments radiation response without adverse effect on hearing in NF2 schwannoma models.
- Computational repositioning and preclinical validation of mifepristone for human vestibular schwannoma.
- Ancestral Adeno-Associated Virus Vector Delivery of Opsins to Spiral Ganglion Neurons: Implications for Optogenetic Cochlear Implants.
- Acute Otitis Media and Associated Complications in United States Emergency Departments.
- Reversible Sensorineural Hearing Loss Associated with Off-Label Use of Transcutaneous Vagal Nerve Stimulator.
- Visualizing the 3D cytoarchitecture of the human cochlea in an intact temporal bone using synchrotron radiation phase contrast imaging.
- Publisher Correction: Computational repositioning and preclinical validation of mifepristone for human vestibular schwannoma.
- The Role of Tumor Necrosis Factor Alpha (TNFα)in Hearing Loss and Vestibular Schwannomas.
- A synthetic AAV vector enables safe and efficient gene transfer to the mammalian inner ear.
- Cochlear Implantation: Vast Unmet Need to Address Deafness Globally.
- Skin Pigmentation and Risk of Hearing Loss in Women.
- A Unified Methodological Framework for Vestibular Schwannoma Research.
- Neonatal Murine Cochlear Explant Technique as an In Vitro Screening Tool in Hearing Research.
- Human Cochlear Histopathology Reflects Clinical Signatures of Primary Neural Degeneration.
- Cochlear Dysfunction is not Common in Human Meningioma of the Internal Auditory Canal.
- Tumor-Penetrating Delivery of siRNA against TNFα to Human Vestibular Schwannomas.
- Energy-efficient waveform for electrical stimulation of the cochlear nerve.