Bioheat Transfer Basis of Human Thermoregulation: Principles and Applications.
Level 5 - mechanism / opinion, no new human data
Narrative review and mechanistic conceptual paper with no new human trial data
PubMed 35833149 · doi:10.1115/1.4053195
What was done
The authors describe the principles of bioheat transfer and human thermoregulation, focusing on the role of arteriovenous anastomoses (AVAs) in glabrous skin (palms and soles) as forced convection heat exchangers. They present a conceptual technology that applies localized heat over the cerebral spine to upregulate peripheral AVA perfusion, paired with heat exchangers on the palms or soles to alter blood temperature before it returns to the core.
What was found
The abstract reports no empirical findings, quantitative measurements, or experimental data.
Why it matters
If validated, non-invasive manipulation of spinal thermoregulatory pathways to drive peripheral AVA perfusion could offer a method for therapeutic and prophylactic core temperature management.
Limits
No human experimental data, sample sizes, or quantitative outcomes are reported in the abstract. The feasibility, safety, and real-world efficacy of the proposed technology remain unverified based solely on this description.
Cited by
- supports The palms of the hands serve as effective thermoregulatory surfaces for the human body, allowing holding cold objects to lower body temperature and reduce sweating and blushing.