Petersen · Frontiers in sports and active living 2021 · narrative review · n=?

Post-exercise Cold Water Immersion Effects on Physiological Adaptations to Resistance Training and the Underlying Mechanisms in Skeletal Muscle: A Narrative Review.

Level 5 - mechanism / opinion, no new human data

Narrative review without systematic search or meta-analysis

PubMed 33898988 · doi:10.3389/fspor.2021.660291 · record verified 2026-08-26

What was done

This narrative review summarized and critiqued published literature evaluating the effects of post-exercise cold-water immersion (CWI) on long-term physiological adaptations to resistance training and examined the underlying acute and chronic skeletal muscle molecular responses.

What was found

The abstract reports no quantitative values or effect estimates. It qualitatively reports that while CWI accelerates acute post-exercise recovery of strength, soreness, inflammation, muscle damage, and fatigue, chronic use attenuates resistance training adaptations including maximal strength, power, and hypertrophy. Endurance training adaptations were reportedly not negatively affected. Mechanistically, CWI appears to attenuate anabolic signaling pathway activation and muscle protein synthesis post-exercise.

Why it matters

Athletes commonly use cold-water immersion to accelerate recovery, but routine application immediately after resistance training may counteract the cellular signals required for muscle growth and strength development.

Limits

This is an unsystematic narrative review with no study count, pooled effect sizes, or formal risk-of-bias assessment provided in the abstract. The underlying molecular evidence is described as limited, and the abstract notes substantial methodological variability across existing primary studies.

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